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Such methodologies should allow for a direct comparison of (i) toxicant emissions, (ii) a broad range of toxicity endpoints and (iii) reductions in toxicant exposure, to ensure that a given cMRTP is equivalent to, or better than, the reference MRTP

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Of these, 38,336 people with HIV (18,241 male, 18,095 female) and 709,358 HIV-negative individuals (298,334 male, 411,024 female) were current smokers

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